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Valerie Tyler is a 28-year-old organization freak who loves her 16-year-old sister Holly. Even if Holly is rambunctious. Spontaneous. Impulsive. Disconcerting. And definitely disorganized. Then Holly moves in with Val, and the sisters discover they may make better siblings than roomies.

Brothers Shawn and Marlon are on the lookout for money and success, though the two are complete opposites. Shawn is responsible and conservative while Marlon is free-spirited and liberal. They are not immune to sibling rivalry, but frequently enjoy being each other's partner in crime.

Half & Half is an American sitcom that aired on UPN from September 23, 2002, to May 15, 2006. The show focuses on the lives of two paternal half-sisters in their twenties who were estranged throughout their childhood, and are finally developing a close relationship. The series is set in San Francisco. It was the second-most-watched show on UPN's Monday night line-up and fourth overall on the network. The show was on The CW's first draft line-up in March 2006, but due to several circumstances—including The CW's contractual obligation to pick up Reba, the uncancelling of All of Us, and the pick-up of the Girlfriends spin-off The Game—Half & Half was left off the final Fall 2006 schedule and ended production. The series has aired in reruns on Global TV in Canada, Trouble in the UK and in local syndication in the United States. It also airs in the United States on TV One.

A fresh and funny take on modern friendship and what one urban family will do to stay friends after the perfect couple who brought them all together break up on their wedding day. The failed wedding forces them all to question their life choices. Then there are Alex and Dave themselves, who strike a truce and must learn to live with the changes their breakup has brought.

The Tanner family's adventures continue as DJ Tanner-Fuller shares a home with her sister Stephanie and friend Kimmy who help raise her three boys.

Chicagoan Frank Gallagher is the proud single dad of six smart, industrious, independent kids, who without him would be... perhaps better off. When Frank's not at the bar spending what little money they have, he's passed out on the floor. But the kids have found ways to grow up in spite of him. They may not be like any family you know, but they make no apologies for being exactly who they are.

This new chapter of “Sex and the City” follows Carrie, Miranda and Charlotte as they navigate the journey from the complicated reality of life and friendship in their 30s to the even more complicated reality of life and friendship in their 50s.

Based on the bestselling book by Candace Bushnell, Sex and the City tells the story of four best friends, all single and in their late thirties, as they pursue their careers and talk about their sex lives, all while trying to survive the New York social scene. 

The Diaz siblings, Lily and Jorge, are on a mission to find love and purpose. They cross paths with seemingly unrelated residents during some of the most heightened days of the year—the holidays.

The owners of a dive bar in Brooklyn, Horace and Pete, along with bar regulars share their experiences and lives with each other while drinking or working at the bar.

Follow the lives of the Roy family as they contemplate their future once their aging father begins to step back from the media and entertainment conglomerate they control.

A former professional dancer, Brooke, and her brother Cary, an aspiring actor, try to find their place in the world while wrestling with their feelings about their 13-year-old brother Chase's sudden rise to internet fame.

Watch Carly, Sam, and Freddie, as they try to balance their everyday 8th grade lives with their newfound fame managing and starring in the most awesome show on the web.

Fifteen-year-old Drake and Josh are schoolmates, but not close friends. Drake views Josh as weird and a bit of a goof. So, imagine Drake's shock when he finds out that this "goof" is about to become his new step-brother and roommate when his mother marries Josh's father. A spin off of The Amanda Show.

When her boyfriend Derwin Davis is chosen as the new third-string wide receiver for the San Diego Sabers, Melanie Barnett decides to attend a local college so she can be with him. While Derwin worries about the plays on the field, Melanie adjusts to her new lifestyle. She gets a play-by-play account of the lives and relationships among NFL wives, girlfriends and mom/managers who use their best game to help their men stay on the field and on their arm.

Ray Barone is a successful sportswriter living on Long Island with his wife Debra, daughter Ally, and twin sons, Geoffrey and Michael. Ray's meddling parents, Frank and Marie, and brother, Robert, live directly across the street.

The offbeat cast and crew of a sports news show deal with professional, personal, and ethical challenges while functioning in a pressure-cooker work environment.

A comedy about two young couples and their outrageously contrasting views on parenting. Greg and Kim Warner struggle on a daily basis to become perfect at the job. Kim is a neurotic, stay-at-home mother, and although her husband, Greg, is a success in his career, his more difficult job is keeping his wife calm as they raise their two young children. While Kim is determined to be the perfect mother and perfect wife and to raise the perfect children, her sister, Christine Hughes, a very down-to-earth mother of two, continually reminds her that life will never be perfect. Christine's husband, Jimmy, often feels compelled to share with his brother-in-law his philosophy about being a husband and a parent while still remaining a man.

In the near future, Sophie tells her son the story of how she met his father: a story that catapults us back to the year 2021 where Sophie and her close-knit group of friends are in the midst of figuring out who they are, what they want out of life, and how to fall in love in the age of dating apps and limitless options.

Rob Brooks, a female record store owner in the rapidly gentrified neighborhood of Crown Heights, Brooklyn revisit past relationships through music and pop culture, while trying to get over her one true love.

Polish immigrant Abel Rosnovski and Boston banker William Lowell Kane are two men born on the same day, and whose lifelong rivalry shapes their empires and families over decades. Their contrasting paths from poverty and wealth lead to a destructive, decades-long feud for power.

Brothers Jack and Tony Finn work together in the same division of the National Serious and Organised Crime Unit. Being the only officers of their kind, they're feared by colleagues and criminals alike. Jack, however, is leading a secret double life – having fallen in love with Tony's wife, Rachel. Forced to put their personal differences aside for the sake of their profession, Jack and Tony investigate the likes of crime families, Triads, gangland killings, extortion and major drug suppliers, all whilst trying to battle with their own demons.

An exclusive group of privileged teens from a posh prep school on Manhattan's Upper East Side whose lives revolve around the blog of the all-knowing albeit ultra-secretive Gossip Girl.

The story of New Jersey-based Italian-American mobster Tony Soprano and the difficulties he faces as he tries to balance the conflicting requirements of his home life and the criminal organization he heads. Those difficulties are often highlighted through his ongoing professional relationship with psychiatrist Jennifer Melfi. The show features Tony's family members and Mafia associates in prominent roles and story arcs, most notably his wife Carmela and his cousin and protégé Christopher Moltisanti.

A stand-up comedian and his three offbeat friends weather the pitfalls and payoffs of life in New York City in the '90s. It's a show about nothing.

Six very different New Yorkers go about their lives without realizing the impact they're having on one another—yet. A mysterious web of coincidences will gradually draw these strangers closer, changing the course of their lives forever.

At Bedford University, six students are brought together in seminar called Sex and the Human Condition.

Hope, a down-to-earth, happily married mother of three has her tidy world turned upside down when her celebrity sister moves in. Faith was living the Hollywood life as a soap opera star before her character was killed off.

Doctor Henry Morgan, New York City’s star medical examiner, has a secret. He doesn't just study the dead to solve criminal cases, he does it to solve the mystery that has eluded him for 200 years—the answer to his own inexplicable immortality. This long life has given Henry remarkable observation skills which impresses his new partner, Detective Jo Martinez. Each week, a new case and their budding friendship will reveal layers of Henry’s long and colorful past. Only his best friend and confidant, Abe knows Henry’s secret.

A modern-day drama about a crime-solving duo that cracks the NYPD's most impossible cases. Following his fall from grace in London and a stint in rehab, eccentric Sherlock escapes to Manhattan where his wealthy father forces him to live with his worst nightmare - a sober companion, Dr. Watson.

In this musical comedy, optimistic high school teacher Will Schuester tries to refuel his own passion while reinventing the high school's glee club and challenging a group of outcasts to realize their star potential as they strive to outshine their singing competition while navigating the cruel halls of McKinley High.

Broad City follows two women throughout their daily lives in New York City, making the smallest and mundane events hysterical and disturbing to watch all at the same time.

Set in downtown New York in 1900, 'The Knick' is centered on the Knickerbocker Hospital and its staff, notably Dr. John Thackery, the hospital's brilliant chief surgeon who pushes medicine's boundaries, pioneering new procedures despite a severe drug addiction.

Six young people from New York City, on their own and struggling to survive in the real world, find the companionship, comfort and support they get from each other to be the perfect antidote to the pressures of life.

If "greatness is thrust upon us," as Winston Churchill once said, then it stands to reason that those who are destined for greatness are rarely aware of it. Take Jack and Bobby McCallister for example: two bright young brothers growing up under the watchful eye of their eccentric single mother Grace McCallister. Grace's personality is a force of nature destined to shape both of these young men's lives and secure one a place in the history books - as President of the United States.

A century-old vampire from New Orleans reunites with an ailing journalist to recount his life of bloodlust and his tumultuous relationship with the rakish Frenchman who turned him.

A gifted young teen tries to survive life with his dimwitted, dysfunctional family.

Jay, Tyler and Will are friends who have spent the last two years in grad school. A simple prank to rollerblade through one of New York City's most famous museums makes Jay and Tyler prime suspects in a terrorist bombing. They're unable to turn to authorities when they realize they can't prove Will even exists. In every photo from the past two years, he has managed to block his face. Who will believe them?

The two part miniseries chronicles the lives and loves of the four March sisters – Jo, Meg, Amy and Beth – growing up during the American Civil War. While their father leaves for battle, the sisters must rely on each other for strength in the face of tragedies both large and small.